Salvia divinorum, often referred to simply as "salvia," is a psychoactive plant native to the cloud forests of Oaxaca, Mexico. It has been used for centuries by indigenous Mazatec shamans in traditional healing ceremonies and rituals.

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The active ingredient in salvia divinorum is salvinorin A, a potent hallucinogen that is believed to interact with the kappa opioid receptors in the brain. When consumed, salvia can induce intense and vivid hallucinations, altered perceptions of time and space, and a sense of detachment from reality.

Salvia divinorum is typically consumed by smoking dried leaves or by chewing fresh leaves. The effects of salvia are generally short-lived, lasting anywhere from a few minutes to an hour or more, depending on the method of consumption and the dosage.

Salvia divinorum is considered a Schedule I controlled substance in the United States, which means it is illegal to possess or use it for recreational purposes. While some people use salvia for its psychoactive effects, it is important to note that the drug can be dangerous, particularly when used in high doses or in combination with other substances. Side effects can include nausea, dizziness, loss of coordination, and psychological distress.

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